Anti-Human CD2 PE

Grouped product items
SizePrice Qty
25 tests
$90.00
100 tests
$210.00

Additional RPA-2.10 Formats

Cat.No.FormatStarting From
04111-25SAFIRE Purified$ 130.00
04111-80APC$ 105.00
04111-60PE$ 90.00
04111-50FITC$ 75.00
04111-40BG Violet 450$ 110.00
Catalog Number : 04111-60

description

The RPA-2.10 monoclonal antibody specifically binds to human CD2, a 50 kDA type I transmembrane glycoprotein. CD2 is expressed on NK cells, thymocytes, T lymphocytes, and B cell subsets. CD2 is involved in cell-cell adhesion, T cell activation, and T cell signaling. Its ligand is CD58 and it is reported to bind to CD48, CD59, and CD15. The RPA-2.10 antibody is reported to be cross-reactive with pigs and non-human primates.

Additional Information

Clone:
RPA-2.10
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest:Adaptive Immunity
Cell Type:T Cells, B Cells, NK and NKT Cells
Application:FC
Clone:RPA-2.10
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Hahn, W. C., Burakoff, S. J., & Bierer, B. E. (1993). Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.The Journal of Immunology150(7), 2607-2619.

Aversa, G. G., Bishop, G. A., Suranyi, M. G., & Hall, B. M. (1987, February). RPA-2.10: an anti-CD2 monoclonal antibody that inhibits alloimmune responses and monitors T cell activation. In Transplantation proceedings (Vol. 19, No. 1 Pt 1, pp. 277-278).

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