Anti-Human CD2 APC
Additional RPA-2.10 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 04111-25 | SAFIRE Purified | $ 130.00 |
| 04111-80 | APC | $ 105.00 |
| 04111-60 | PE | $ 90.00 |
| 04111-50 | FITC | $ 75.00 |
| 04111-40 | BG Violet 450 | $ 110.00 |
Catalog Number : 04111-80
description
The RPA-2.10 monoclonal antibody specifically binds to human CD2, a 50 kDA type I transmembrane glycoprotein. CD2 is expressed on NK cells, thymocytes, T lymphocytes, and B cell subsets. CD2 is involved in cell-cell adhesion, T cell activation, and T cell signaling. Its ligand is CD58 and it is reported to bind to CD48, CD59, and CD15. The RPA-2.10 antibody is reported to be cross-reactive with pigs and non-human primates.
Additional Information
Clone: | RPA-2.10 |
Format: | APC |
Applications: | FC |
Reactivity: | Human |
Isotype: | Mouse IgG1, kappa |
| Research Interest: | Adaptive Immunity |
|---|---|
| Cell Type: | T Cells, B Cells, NK and NKT Cells |
| Application: | FC |
| Clone: | RPA-2.10 |
Preparation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Hahn, W. C., Burakoff, S. J., & Bierer, B. E. (1993). Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.The Journal of Immunology, 150(7), 2607-2619. Aversa, G. G., Bishop, G. A., Suranyi, M. G., & Hall, B. M. (1987, February). RPA-2.10: an anti-CD2 monoclonal antibody that inhibits alloimmune responses and monitors T cell activation. In Transplantation proceedings (Vol. 19, No. 1 Pt 1, pp. 277-278). |