Anti-Human CD1a Biotin
Catalog Number : 03111-30
description
The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein. It is expressed on dendritic cells, Langerhans cells, and cortical thymocytes. CD1a plays a role in antigen presentation and ,like MHC Class I, it non-covalently associates with Beta2-microglobulin.
Additional Information
Clone: | HI149 |
Format: | Biotin |
Applications: | FC |
Reactivity: | Human |
Isotype: | Mouse IgG1, kappa |
| Research Interest: | Adaptive Immunity, Innate Immunity |
|---|---|
| Cell Type: | T Cells, Dendritic Cells |
| Application: | FC |
| Clone: | HI149 |
Preparation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted biotin was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Hanau, D., Schmitt, D. A., Bieber, T., Schmitt, D., & Cazenave, J. P. (1990). Possible mechanism of action of CD1a antigens. Journal of investigative dermatology, 95(5), 503-505. |