Anti-Human CD16 FITC

Grouped product items
Size Price Qty
25 tests
100 tests

Additional CB16 Formats

Cat.No. Format Starting From
08211-50 FITC $ 90.00
08211-25 SAFIRE Purified $ 410.00
08211-80 APC $ 120.00
08211-77 PE-Cyanine7 $ 155.00
Catalog Number : 08211-50


The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.

Additional Information

Mouse IgG1, kappa
Research Interest: Innate Immunity
Cell Type: Macrophage / Monocyte, NK and NKT Cells
Application: FC
Clone: CB16
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Deaglio, S., Zubiaur, M., Gregorini, A., Bottarel, F., Ausiello, C. M., Dianzani, U., ... & Malavasi, F. (2002). Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells. Blood99(7), 2490-2498.

Peruzzi, G., Femnou, L., Gil-Krzewska, A., Borrego, F., Weck, J., Krzewski, K., & Coligan, J. E. (2013). Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. The Journal of Immunology191(4), 1883-1894.

Wirthmueller, U., Kurosaki, T., Murakami, M. S., & Ravetch, J. V. (1992). Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain. The Journal of experimental medicine175(5), 1381-1390.

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