Anti-Human CD14 PE

Grouped product items
Size Price Qty
25 tests
$100.00
100 tests
$215.00

Additional 61D3 Formats

Cat.No. Format Starting From
06211-50 FITC $ 80.00
06211-70 PerCP-Cyanine5.5 $ 190.00
06211-80 APC $ 120.00
06211-25 SAFIRE Purified $ 275.00
06211-40 BG Violet 450 $ 100.00
06211-60 PE $ 100.00
Catalog Number : 06211-60

description

The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
product image
Human peripheral blood monocytes were stained with PE 61D3 with relevant isotype control in Gray

Additional Information

Clone:
61D3
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity
Cell Type: Macrophage / Monocyte
Application: FC
Clone: 61D3
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature392(6675), 505-509.

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