Anti-Human CD137L (4-1BB Ligand) APC
Catalog Number : 19461-80
The 4H3 monoclonal antibody bind to human CD137 Ligand or 4-1BBL, a type II membrane protein in the TNF superfamily. It is mainly expressed on antigen presenting cells, and activated B and T cells. Ligation of 4-1BB on T cells and natural killer cells induces cell activation, promotes survival, and enhances effector functions.
Mouse IgG1, kappa
|Research Interest:||Adaptive Immunity|
|Cell Type:||B Cells, Macrophage / Monocyte, T Cells|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Jung, H. W., Choi, S. W., Choi, J. I., & Kwon, B. S. (2004). Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis. Experimental & molecular medicine, 36(1), 13.