Anti-Human CD163 APC

Grouped product items
SizePrice Qty
25 tests
$140.00
100 tests
$350.00

Additional GHI/61 Formats

Cat.No.FormatStarting From
15711-60PE$ 120.00
15711-77PE-Cyanine7$ 165.00
15711-80APC$ 140.00
Catalog Number : 15711-80

description

The GHI/61 antibody specifically reacts with human CD163, high affinity scavenger receptor for the hemoglobin-haptoglobin complex and a common marker for cells of the monocyte/macrophage lineage. It is reported to be involved in the regulation of cytokine production and functions as the innate immune sensor for gram-positive and gram-negative bacteria.

Additional Information

Clone:
GHI/61
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest:Innate Immunity
Cell Type:Macrophage / Monocyte
Application:FC
Clone:GHI/61
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Pulford, K., Micklem, K., McCarthy, S., Cordell, J., Jones, M., & Mason, D. Y. (1992). A monocyte/macrophage antigen recognized by the four antibodies GHI/61, Ber-MAC3, Ki-M8 and SM4. Immunology75(4), 588.

Ritter, M., Buechler, C., Langmann, T., Orso, E., Klucken, J., & Schmitz, G. (1999). The scavenger receptor CD163: regulation, promoter structure and genomic organization. Pathobiology67(5-6), 257-261.

Maniecki, M. B., Etzerodt, A., Moestrup, S. K., Møller, H. J., & Graversen, J. H. (2011). Comparative assessment of the recognition of domain-specific CD163 monoclonal antibodies in human monocytes explains wide discrepancy in reported levels of cellular surface CD163 expression. Immunobiology216(8), 882-890.

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