Favipiravir
Catalog Number : 2599693
description
Favipiravir is a potent and selective inhibitor of RNA-dependent RNA polymerase of RNA viruses. It is reported to be effective against a wide range of types and subtypes of viruses. Favipiravir is metabolized into its active form of favipiravir-ribofuranosyl-5'-triphosphate (favipiravir-RTP). It is currently being researched as a potential treatment for COVID-19
Additional Information
Applications: | FA |
Synonyms: | T 705, T-705, Favilavir, Avigan |
Formulation: | Crystalline solid |
Chemical Name: | 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide |
Molecular Formula: | C5H4FN3O2 |
Molecular Weight: | 157.1 |
CAS Number | 259793-96-9 |
Purity: | 98% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Furuta, Y., Gowen, B. B., Takahashi, K., Shiraki, K., Smee, D. F., & Barnard, D. L. (2013). Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral research, 100(2), 446-454.
Rocha-Pereira, J., Jochmans, D., Dallmeier, K., Leyssen, P., Nascimento, M. S. J., & Neyts, J. (2012). Favipiravir (T-705) inhibits in vitro norovirus replication. Biochemical and biophysical research communications, 424(4), 777-780.
Chen, C., Huang, J., Cheng, Z., Wu, J., Chen, S., Zhang, Y., ... & Yin, P. (2020). Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial. medRxiv. |