EHNA hydrochloride

Grouped product items
Size Price Qty
5mg
$35.00
25mg
$140.00
Catalog Number : 5833857

description

EHNA is a potent adenosine deaminase and phosphodiesterase type 2 inhibitor. It is reported to be used to inhibit spontaneous differentiation of stem and neuronal cells.

Additional Information

Applications:
FA
Synonyms:
NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride
Formulation:
Crystalline solid
Chemical Name:
(2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride
Molecular Formula:

C14H23N5O HCl

Molecular Weight:
313.8
CAS Number
58337-38-5
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Baker, D. C., Hanvey, J. C., Hawkins, L. D., & Murphy, J. (1981). Identification of the bioactive enantiomer of erthro-3-(adenin-9-YL)-2-nonanol (EHNA), a semi-tight binding inhibitor of adenosine deaminase. Biochemical pharmacology,30(10), 1159-1160.

Woodson, J. C., Minor, T. R., & Soames Job, R. F. (1998). Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats. Behavioral neuroscience112(2), 399.

Burton, P., Adams, D., Abraham, A., Allcock, R., Jiang, Z., McCahill, A., ... & Mountford, J. (2010). Erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochem. J432, 575-584.

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