EHNA hydrochloride
description
Additional Information
Applications:
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FA
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Synonyms:
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NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride
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Formulation:
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Crystalline solid
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Chemical Name:
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(2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride
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Molecular Formula:
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C14H23N5O HCl |
Molecular Weight: |
313.8
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CAS Number
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58337-38-5
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Baker, D. C., Hanvey, J. C., Hawkins, L. D., & Murphy, J. (1981). Identification of the bioactive enantiomer of erthro-3-(adenin-9-YL)-2-nonanol (EHNA), a semi-tight binding inhibitor of adenosine deaminase. Biochemical pharmacology,30(10), 1159-1160. Woodson, J. C., Minor, T. R., & Soames Job, R. F. (1998). Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats. Behavioral neuroscience, 112(2), 399. Burton, P., Adams, D., Abraham, A., Allcock, R., Jiang, Z., McCahill, A., ... & Mountford, J. (2010). Erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochem. J, 432, 575-584. |