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Dibutyryl-cAMP, sodium salt



Catalog Number : 1698950

Description

Dibutyryl-cAMP is a cell-permeable activator of cAMP-dependent protein kinases and phosphodiesterase inhibitor. It mimics endogenous cyclic adenosine monophosphate (cAMP). Dibutyryl-cAMP is reported to induce apoptosis in vascular smooth muscle cells and induce neurite growth.
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Additional Information

Applications:
FA
Synonyms:
Bucladesine sodium salt, Actosin, MLS001148197
Formulation:
Crystalline solid
Chemical Name:
sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate
Molecular Formula:

C18H23N5O8P Na

Molecular Weight:
491.4
CAS Number
16980-89-5
Purity:
≥95%
Storage Conditions:
Product should be kept at -20°C.
References:

Kahn, A. M., Dolson, G. M., Hise, M. K., Bennett, S. C., & Weinman, E. J. (1985). Parathyroid hormone and dibutyryl cAMP inhibit Na+/H+ exchange in renal brush border vesicles. American Journal of Physiology-Renal Physiology248(2), F212-F218.

Leonard, J. L. (1988). Dibutyryl cAMP induction of type II 5′ deiodinase activity in rat brain astrocytes in culture. Biochemical and biophysical research communications151(3), 1164-1172.

Rundfeldt, C., Steckel, H., Sörensen, T., & Wlaz, P. (2012). The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation. Archives of dermatological research304(4), 313-317.


Availability: In stock

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50mg
$50.00
250mg
$220.00