Dexamethasone
Catalog Number : 5000222
description
Dexamethasone is a synthetic anti-inflammatory and immunosuppressant steroid. It has a stronger affinity for the glucocorticoid receptor than the natural hydrocortisone ligand. Dexamethasone is reported to inhibit mature dendritic cell differentiation and to promote the differentiation of human mesenchymal cells.
Additional Information
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Applications:
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FA
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Synonyms:
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Decaject, Decameth, Decaspray, Dexasone, Hexadecadrol
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Formulation:
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Crystalline solid
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Chemical Name:
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(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
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Molecular Formula:
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C22H29FO5 |
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Molecular Weight: |
392.5
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CAS Number
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50-02-2
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Haynesworth, S. E., Baber, M. A., & Caplan, A. I. (1996). Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α. Journal of cellular physiology, 166(3), 585-592. Han, J., Thompson, P., & Beutler, B. (1990). Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. The Journal of experimental medicine, 172(1), 391-394. Larsson, E. L. (1980). Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process. The Journal of Immunology, 124(6), 2828-2833. |