D-AP5
Catalog Number : 7908985
description
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. D-AP5 is reported to be the most active form of AP5 and is used in the research of synaptic plasticity.
Additional Information
Applications:
|
FA
|
Synonyms:
|
2-APV, 5 Phosphononorvaline
|
Formulation:
|
Crystalline solid
|
Chemical Name:
|
(2R)-2-amino-5-phosphonopentanoic acid
|
Molecular Formula:
|
C5H12NO5P |
Molecular Weight: |
197.1
|
CAS Number
|
79055-68-8
|
Purity:
|
≥95%
|
Storage Conditions:
|
Product should be kept at -20°C.
|
References:
|
Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus, 9(2), 118-136. Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience,9(9), 3040-3057. Davies, J., & Watkins, J. C. (1982). Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.Brain research, 235(2), 378-386. |