CHIR 99021
description
Additional Information
Applications:
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FA
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Synonyms:
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Chir99021, CHEMBL412142, GSK-3 Inhibitor XVI, AGN-PC-0MWAEX
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Formulation:
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Crystalline solid
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Chemical Name:
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6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile
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Molecular Formula:
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C22H18Cl2N8 |
Molecular Weight: |
465.3
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CAS Number
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252917-06-9
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Purity:
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≥95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Li, W., Wei, W., Zhu, S., Zhu, J., Shi, Y., Lin, T., ... & Ding, S. (2009). Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell stem cell, 4(1), 16-19. Ye, S., Tan, L., Yang, R., Fang, B., Qu, S., Schulze, E. N., ... & Li, P. (2012). Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PloS one,7(4), e35892. Wu, Y., Ai, Z., Yao, K., Cao, L., Du, J., Shi, X., ... & Zhang, Y. (2013). CHIR99021 promotes self-renewal of mouse embryonic stem cells by modulation of protein-encoding gene and long intergenic non-coding RNA expression. Experimental cell research, 319(17), 2684-2699. |