Captopril
Catalog Number : 6258621
description
Captopril is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II and prevents the degradation of vasodilatory prostaglandins. Captopril is also a reversible inhibitor of leukotriene hydrolase and exhibits antihypertensive properties. It is currently being researched regarding its interaction with proteins that interact with SARS-CoV-2
Additional Information
Applications: | FA |
Synonyms: | Lopirin, Capoten, SQ 14,225 |
Formulation: | Crystalline solid |
Chemical Name: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid |
Molecular Formula: | C9H15NO3S |
Molecular Weight: | 217.3 |
CAS Number | 62571-86-2 |
Purity: | 98% |
Storage Conditions: | Product should be kept at -20°C. |
References: | Brogden, R. N., Todd, P. A., & Sorkin, E. M. (1988). Captopril. Drugs, 36(5), 540-600. Vidt, D. G., Bravo, E. L., & Fouad, F. M. (1982). Captopril. New England Journal of Medicine, 306(4), 214-219. Hirooka, Y., Imaizumi, T., Masaki, H., Ando, S. I., Harada, S., Momohara, M., & Takeshita, A. (1992). Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients. Hypertension, 20(2), 175-180. |