cAMP
Catalog Number : 6099240
description
cAMP is an adenosine triphosphate (ATP) derivative and used for intracellular signal transduction. cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase. cAMP is a second messenger that can transfer hormones such as adrenaline and glucagon that cannot pass through the plasma membrane. It is also reported to be involved in the activation of protein kinases and the regulation of calcium channels.
Additional Information
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Applications:
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FA
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Synonyms:
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Cyclic AMP, Adenosine cyclic monophosphate, Cyclic adenosine monophosphate
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Formulation:
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Crystalline solid
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Chemical Name:
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(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
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Molecular Formula:
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C10H12N5O6P |
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Molecular Weight: |
329.2
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CAS Number
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60-92-4
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Bourne, H. R., Weinstein, Y., Melmon, K. L., Lichtenstein, L. M., Henney, C. S., & Shearer, G. M. (1974). Modulation of inflammation and immunity by cyclic AMP. Science, 184(4132), 19-28. De Rooij, J., Zwartkruis, F. J., Verheijen, M. H., Cool, R. H., Nijman, S. M., Wittinghofer, A., & Bos, J. L. (1998). Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature, 396(6710), 474-477. DiFrancesco, D., & Tortora, P. (1991). Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature, 351(6322), 145-147. |