BAY 11-7082
description
Additional Information
|
Applications:
|
FA
|
|
Synonyms:
|
(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile
|
|
Formulation:
|
Crystalline solid
|
|
Chemical Name:
|
(E)-3-(4-methylphenyl)sulfonylprop-2-enenitrile
|
|
Molecular Formula:
|
C10H9NO2S |
|
Molecular Weight: |
207.3
|
|
CAS Number
|
19542-67-7
|
|
Purity:
|
≥98%
|
|
Storage Conditions:
|
Product should be kept at -20°C.
|
|
References:
|
Mori, N., Yamada, Y., Ikeda, S., Yamasaki, Y., Tsukasaki, K., Tanaka, Y., ... & Fujii, M. (2002). Bay 11-7082 inhibits transcription factor NF-κB and induces apoptosis of HTLV-I–infected T-cell lines and primary adult T-cell leukemia cells. Blood, 100(5), 1828-1834. Lappas, M., Yee, K., Permezel, M., & Rice, G. E. (2005). Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-κB and IκB kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. Endocrinology, 146(3), 1491-1497. García, M. G., Alaniz, L., Lopes, E. C., Blanco, G., Hajos, S. E., & Alvarez, E. (2005). Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines. Leukemia research, 29(12), 1425-1434. |