Anti-Rat CD4 FITC
Catalog Number : 06113-50
description
The OX35 monoclonal antibody specifically binds to rat CD4, a 55kD glycoprotein with four extracellular immunoglobulin-like domains also known as T4. It is expressed on the surface of most thymocytes, T-helper cells, monocytes, and macrophages, and some dendritic cells. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II).
Additional Information
Clone:
|
OX35
|
Format:
|
FITC
|
Applications:
|
FC
|
Reactivity:
|
Rat
|
Isotype:
|
Mouse IgG2a, kappa
|
Research Interest: | Adaptive Immunity |
---|---|
Cell Type: | T Cells, T Regulatory Cells, Macrophage / Monocyte |
Application: | FC |
Clone: | OX35 |
Preparation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
References:
|
Jefferies, W. A., Green, J. R., & Williams, A. F. (1985). Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages. Journal of Experimental Medicine, 162(1), 117-127. Crocker, P. R., Jefferies, W. A., Clark, S. J., Chung, L. P., & Gordon, S. I. A. M. O. N. (1987). Species heterogeneity in macrophage expression of the CD4 antigen. Journal of Experimental Medicine, 166(2), 613-618. Bañuls, M. P., Alvarez, A., Ferrero, I., Zapata, A., & Ardavin, C. (1993). Cell-surface marker analysis of rat thymic dendritic cells. Immunology, 79(2), 298. |