Anti-Rat CD4 FITC

Grouped product items
Size Price Qty
50 ug
$140.00
500 ug
$470.00

Additional OX35 Formats

Cat.No. Format Starting From
06113-50 FITC $ 140.00
06113-60 PE $ 285.00
Catalog Number : 06113-50

description

The OX35 monoclonal antibody specifically binds to rat CD4, a 55kD glycoprotein with four extracellular immunoglobulin-like domains also known as T4. It is expressed on the surface of most thymocytes, T-helper cells, monocytes, and macrophages, and some dendritic cells. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II).

Additional Information

Clone:
OX35
Format:
FITC
Applications:
FC
Reactivity:
Rat
Isotype:
Mouse IgG2a, kappa
Research Interest: Adaptive Immunity
Cell Type: T Cells, T Regulatory Cells, Macrophage / Monocyte
Application: FC
Clone: OX35
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Jefferies, W. A., Green, J. R., & Williams, A. F. (1985). Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages. Journal of Experimental Medicine162(1), 117-127.

Crocker, P. R., Jefferies, W. A., Clark, S. J., Chung, L. P., & Gordon, S. I. A. M. O. N. (1987). Species heterogeneity in macrophage expression of the CD4 antigen. Journal of Experimental Medicine166(2), 613-618.

Bañuls, M. P., Alvarez, A., Ferrero, I., Zapata, A., & Ardavin, C. (1993). Cell-surface marker analysis of rat thymic dendritic cells. Immunology79(2), 298.

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