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Anti-Mouse/Rat CD29 SAFIRE Purified



Catalog Number : 11312-25

Description

The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.

Additional Information

Clone:
HMb1-1
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Angiogenesis
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Ridger, V. C., Wagner, B. E., Wallace, W. A., & Hellewell, P. G. (2001). Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation. The Journal of Immunology,166(5), 3484-3490.

Noto, K., Kato, K., Okumura, K., & Yagita, H. (1995). Identification and functional characterization of mouse CD29 with a mAb. International immunology7(5), 835-842.

Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... & Colombo, M. P. (2008). Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis. Cancer research68(21), 9050-9059.


Availability: In stock

Size Price Qty
500 ug
$360.00
Additional HMb1-1 Formats
Cat.No. Format Starting From
11312-60PE $ 130.00
11312-25SAFIRE Purified $ 360.00
11312-50FITC $ 105.00
11312-80APC $ 120.00