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Anti-Mouse CD8b APC



Catalog Number : 10132-80

Description

The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.

Additional Information

Clone:
H35-17.2
Format:
APC
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG2b, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Lefrancois, L. (1991). Phenotypic complexity of intraepithelial lymphocytes of the small intestine. The Journal of Immunology147(6), 1746-1751.

Walker, I. D., Murray, B. J., Hogarth, P. M., Kelso, A., & McKenzie, I. F. (1984). Comparison of thymic and peripheral T cell Ly‐2/3 antigens. European journal of immunology14(10), 906-910.

THOMA-USZYNSKI, S., LADEL, C., & KAUFMANN, S. (1997). Abscess formation in Listeria monocytogenes-infected γδ T cell deficient mouse mutants involves αβ T cells. Microbial pathogenesis22(2), 123-128.


Availability: In stock

Size Price Qty
50 ug
$160.00
Additional H35-17.2 Formats
Cat.No. Format Starting From
10132-60PE $ 90.00
10132-80APC $ 160.00