Anti-Mouse CD83 PE
Catalog Number : 05912-60
description
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.
Additional Information
Clone:
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Michel17
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Format:
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PE
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Applications:
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FC
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Reactivity:
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Mouse
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Isotype:
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Rat IgG1
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Research Interest: | Innate Immunity |
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Cell Type: | Dendritic Cells |
Application: | FC |
Clone: | Michel17 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Moré, S., Fleischer, B., & von Bonin, A. (2000). Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells. International immunology, 12(9), 1347-1351. Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., & Von Bonin, A. (2003). Enhanced Activation of CD83‐Positive T Cells*. Scandinavian journal of immunology, 58(3), 306-311. Breloer, M., & Fleischer, B. (2008). CD83 regulates lymphocyte maturation, activation and homeostasis. Trends in immunology, 29(4), 186-194. |