Anti-Mouse CD69 FITC

Grouped product items
Size Price Qty
25 ug
$50.00
100 ug
$130.00

Additional H1.2F3 Formats

Cat.No. Format Starting From
11712-50 FITC $ 50.00
11712-80 APC $ 165.00
11712-60 PE $ 205.00
11712-25 SAFIRE Purified $ 390.00
11712-77 PE-Cyanine7 $ 65.00
Catalog Number : 11712-50

description

The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
product image
C57Bl/6 splenocytes were stimulated overnight with Concanavalin A and stained with FITC H1.2F3 with relevant isotype control in Red.

Additional Information

Clone:
H1.2F3
Format:
FITC
Applications:
FC
Reactivity:
Mouse
Isotype:
Armenian Hamster IgG
Research Interest: Adaptive Immunity
Cell Type: B Cells, NK and NKT Cells, T Cells
Application: FC
Clone: H1.2F3
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., & Corradin, S. B. (1997). Expression and function of the early activation antigen CD69 in murine macrophages. Journal of leukocyte biology62(3), 349-355.

Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., & Shevach, E. M. (1988). Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. The Journal of Immunology141(2), 369-376.

Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., & Cohen, P. L. (1993). Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes. The Journal of Immunology150(2), 673-682.

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