Anti-Mouse CD38 SAFIRE Purified
Additional 90 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 10412-25 | SAFIRE Purified | $ 500.00 |
Catalog Number : 10412-25
description
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Additional Information
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Clone:
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90
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Format:
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SAFIRE Purified
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Applications:
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FC, FA
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2a, kappa
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| Cell Type: | B Cells, NK and NKT Cells, Macrophage / Monocyte, T Cells |
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| Application: | FC, FA |
| Clone: | 90 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Oliver, A. M., Martin, F., & Kearney, J. F. (1997). Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells. The Journal of Immunology, 158(3), 1108-1115. Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., & Zlotnik, A. (1995). CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of αβ TCR+ CD4− CD8− thymocytes. International immunology, 7(2), 213-221. Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., & Howard, M. (1995). Murine CD38: an immunoregulatory ectoenzyme. Immunology today,16(10), 469-473. |