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Anti-Mouse CD38 SAFIRE Purified



Catalog Number : 10412-25

Description

The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.

Additional Information

Clone:
90
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Mouse
Isotype:
Mouse IgG2a, kappa
Cell Type: B Cells, NK and NKT Cells, Monocytes and Macrophages, T Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Oliver, A. M., Martin, F., & Kearney, J. F. (1997). Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells. The Journal of Immunology158(3), 1108-1115.

Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., & Zlotnik, A. (1995). CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of αβ TCR+ CD4− CD8− thymocytes. International immunology7(2), 213-221.

Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., & Howard, M. (1995). Murine CD38: an immunoregulatory ectoenzyme. Immunology today,16(10), 469-473.


Availability: In stock

Size Price Qty
500 ug
$320.00
Additional 90 Formats
Cat.No. Format Starting From
10412-25SAFIRE Purified $ 320.00