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Anti-Mouse CD339 (Jagged 1) PE



Catalog Number : 41412-60

Description

The HMJ1-29 monoclonal antibody reacts with mouse and rat CD339 (Jagged 1), a type 1 transmembrane Notch receptor ligand. It is expressed by macrophages and certain stromal, epithelial, dendritic, and thymic lymphoid cells. It has been reported to be play a role in Treg induction, Th2 polarization, neurogenesis, and cardiovascular development.

Additional Information

Clone:
HMJ1-29
Format:
PE
Applications:
FC
Reactivity:
Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Stem Cell Research, Angiogenesis
Cell Type: Monocytes and Macrophages, Stem Cells, Dendritic Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Sekine, C., Moriyama, Y., Koyanagi, A., Koyama, N., Ogata, H., Okumura, K., & Yagita, H. (2009). Differential regulation of splenic CD8− dendritic cells and marginal zone B cells by Notch ligands. International immunology21(3), 295-301.

Yamaguchi, E., Chiba, S., Kumano, K., Kunisato, A., Takahashi, T., Takahashi, T., & Hirai, H. (2002). Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice. Immunology letters81(1), 59-64.

Elyaman, W., Bradshaw, E. M., Wang, Y., Oukka, M., Kivisäkk, P., Chiba, S., ... & Khoury, S. J. (2007). JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis. The Journal of Immunology179(9), 5990-5998.


Availability: In stock

Size Price Qty
25 ug
$170.00
100 ug
$330.00
Additional HMJ1-29 Formats
Cat.No. Format Starting From
41412-60PE $ 170.00