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Anti-Mouse CD289 (TLR9) FITC

Catalog Number : 31912-50


The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.

Additional Information

Rat IgG2a
Research Interest: Innate Immunity
Cell Type: Monocytes and Macrophages, Dendritic Cells
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Kubo, T., Uchida, Y., Watanabe, Y., Abe, M., Nakamura, A., Ono, M., ... & Takai, T. (2009). Augmented TLR9-induced Btk activation in PIR-B–deficient B-1 cells provokes excessive autoantibody production and autoimmunity. The Journal of experimental medicine206(9), 1971-1982.

Fukata, M., Breglio, K., Chen, A., Vamadevan, A. S., Goo, T., Hsu, D., ... & Abreu, M. T. (2008). The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.The Journal of Immunology180(3), 1886-1894.

Miranda-Hernandez, S., Gerlach, N., Fletcher, J. M., Biros, E., Mack, M., Körner, H., & Baxter, A. G. (2011). Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. The Journal of Immunology187(2), 791-804.

Availability: In stock

Size Price Qty
25 ug
100 ug
Additional M9.D6 Formats
Cat.No. Format Starting From
31912-50FITC $ 130.00