Anti-Mouse CD20 SAFIRE Purified
Additional AISB12 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 02312-25 | SAFIRE Purified | $ 210.00 |
Catalog Number : 02312-25
description
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Additional Information
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Clone:
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AISB12
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Format:
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SAFIRE Purified
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Applications:
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FC, FA
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Reactivity:
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Mouse
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Isotype:
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Rat IgG2a
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| Research Interest: | Adaptive Immunity |
|---|---|
| Cell Type: | B Cells |
| Application: | FC, FA |
| Clone: | AISB12 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., & Tedder, T. F. (2004). The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor–dependent mechanisms during anti-CD20 antibody immunotherapy. The Journal of experimental medicine,199(12), 1659-1669. Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... & Tedder, T. F. (2004). Mouse CD20 expression and function. International immunology, 16(1), 119-129. Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... & Yi, Q. (2012). Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma. Blood, 119(1), 161-169. |