Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Anti-Mouse CD2 PE



Catalog Number : 04112-60

Description

The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein. CD2 is expressed on B cells, T cells, NK cells, and thymocytes and its ligand is CD48. It may be involved in immunoregulation, thymocyte maturation, and T-cell activation. The RM2-5 antibody has been reported to block CD2 mediated cell to cell adhesion.

Additional Information

Clone:
RM2-5
Format:
PE
Applications:
FC
Reactivity:
Mouse
Isotype:
Rat IgG2b, lambda
Research Interest: Adaptive Immunity
Cell Type: B Cells, NK and NKT Cells, T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Yagita, H., Nakamura, T., Karasuyama, H., & Okumura, K. (1989). Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.Proceedings of the National Academy of Sciences86(2), 645-649.

Nakamura, T. E. T. S. U. Y. A., Takahashi, K. A. Z. U. H. I. S. A., Fukazawa, T. O. H. R. U., Koyanagi, M. A. K. O. T. O., Yokoyama, A., Kato, H., ... & Okumura, K. (1990). Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. The Journal of Immunology145(11), 3628-3634.

Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... & Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. The Journal of experimental medicine176(5), 1241-1249.


Availability: In stock

Size Price Qty
25 ug
$75.00
100 ug
$200.00
Additional RM2-5 Formats
Cat.No. Format Starting From
04112-60PE $ 75.00
04112-50FITC $ 55.00
04112-25SAFIRE Purified $ 145.00