Anti-Mouse CD180 (RP-105) SAFIRE Purified
Additional RP/14 Formats
| Cat.No. | Format | Starting From |
|---|
Catalog Number : 12912-25
description
The RP/14 monoclonal antibody binds to mouse CD180, a 105kDA cell surface molecule consisting of extracellular leucine rich repeats (LCC) and a short cytoplasmic tail also known as Bgp-95 and RP105. CD180 is expressed on B cells, dendritic cells, monocytes, and macrophages. It forms a cell surface receptor complex with MD-1 and with TLR4 is involved with the recognition of bacterial lipopolysaccharide (LPS).
Additional Information
Clone: | RP/14 |
Format: | SAFIRE Purified |
Applications: | FC, FA |
Reactivity: | Mouse |
Isotype: | Rat IgG2a, kappa |
| Research Interest: | Innate Immunity, Apoptosis |
|---|---|
| Cell Type: | B Cells, Macrophage / Monocyte, Dendritic Cells |
| Application: | FC, FA |
| Clone: | RP/14 |
Preparation: | The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. |
Formulation: | Phosphate-buffered aqueous solution, ph7.2. |
References: | Miyake, K., Shimazu, R., Kondo, J., Niki, T., Akashi, S., Ogata, H., ... & Kimoto, M. (1998). Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. The Journal of Immunology,161(3), 1348-1353. Miyake, K., Yamashita, Y., Ogata, M., Sudo, T., & Kimoto, M. (1995). RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. The Journal of Immunology, 154(7), 3333-3340. Chan, V. W., Mecklenbräuker, I., Su, I. H., Texido, G., Leitges, M., Carsetti, R., ... & Tarakhovsky, A. (1998). The molecular mechanism of B cell activation by toll-like receptor protein RP-105. The Journal of experimental medicine,188(1), 93-101. |