Anti-Mouse CD160 SAFIRE Purified

Grouped product items
Size	Price	Qty
500ug	$525.00

Additional CNX46-3 Formats

Cat.No.	Format	Starting From
12712-25	SAFIRE Purified	$ 525.00

Catalog Number : 12712-25

description

The CNX46-3 monoclonal antibody specifically binds to mouse CD160, a glycosyolphosphatidylinositol (GPI)-anchored membrane glycoprotein. It is reported to regulate NK cell activation and is expressed on a subset of T, NKT, NK cells, and all intestinal intraepithelial lymphocytes. CD160 broadly binds to classical and nonclassical MHC class I molecules.

Additional Information

Clone:	CNX46-3
Format:	SAFIRE Purified
Applications:	FC, FA, IP, WB
Reactivity:	Mouse
Isotype:	Rat IgG2a, kappa
Research Interest:	Innate Immunity, Angiogenesis
Cell Type:	B Cells, T Cells, NK and NKT Cells
Application:	FC, FA, IP, WB
Clone:	CNX46-3
Preparation:	The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Formulation:	Phosphate-buffered aqueous solution, ph7.2.
References:	Maeda, M., Carpenito, C., Russell, R. C., Dasanjh, J., Veinotte, L. L., Ohta, H., ... & Takei, F. (2005). Murine CD160, Ig-like receptor on NK cells and NKT cells, recognizes classical and nonclassical MHC class I and regulates NK cell activation. The Journal of Immunology, 175(7), 4426-4432. Anumanthan, A., Bensussan, A., Boumsell, L., Christ, A. D., Blumberg, R. S., Voss, S. D., ... & Freeman, G. J. (1998). Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. The Journal of Immunology, 161(6), 2780-2790. Fons, P., Chabot, S., Cartwright, J. E., Lenfant, F., L'Faqihi, F., Giustiniani, J., ... & Le Bouteiller, P. (2006). Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells. Blood, 108(8), 2608-2615.