Anti-Mouse CD134 (OX40) PE
Catalog Number : 16412-60
description
The OX-86 monoclonal antibody reacts with mouse CD134 (OX40), a type I transmembrane glycoprotein in the TNF superfamily. It is expressed on activated T lymphocytes and enhances cell survival.
Additional Information
Clone:
|
OX-86
|
Format:
|
PE
|
Applications:
|
FC
|
Reactivity:
|
Mouse
|
Isotype:
|
Rat IgG1, kappa
|
Research Interest: | Adaptive Immunity |
---|---|
Cell Type: | T Cells |
Application: | FC |
Clone: | OX-86 |
Preparation:
|
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
|
Formulation:
|
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
|
References:
|
Bansal-Pakala, P., Jember, A. G. H., & Croft, M. (2001). Signaling through OX40 (CD134) breaks peripheral T-cell tolerance. Nature medicine, 7(8), 907. Rogers, P. R., & Croft, M. (2000). CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen. The Journal of Immunology, 164(6), 2955-2963. Gramaglia, I., Jember, A., Pippig, S. D., Weinberg, A. D., Killeen, N., & Croft, M. (2000). The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. The Journal of Immunology, 165(6), 3043-3050. |