Anti-Mouse CD127 (IL-7Ra) APC

Catalog Number : 19212-80

Description

The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.

The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.

Additional Information

Clone:	A7R34
Format:	APC
Applications:	FC
Reactivity:	Mouse
Isotype:	Rat IgG2a, kappa
Research Interest:	Adaptive Immunity
Cell Type:	B Cells, T Cells, Treg cells
Preparation:	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:	Sudo, T., Nishikawa, S. A. T. O. M. I., Ohno, N. O. R. I. K. O., Akiyama, N. A. O. K. O., Tamakoshi, M. A. S. A. T. A. D. A., & Yoshida, H. I. S. A. H. I. R. O. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes. Proceedings of the National Academy of Sciences, 90(19), 9125-9129. Hashi, H., Yoshida, H., Honda, K., Fraser, S., Kubo, H., Awane, M., ... & Nishikawa, S. I. (2001). Compartmentalization of Peyer’s patch anlagen before lymphocyte entry. The Journal of Immunology, 166(6), 3702-3709. Okuno, Y., Iwasaki, H., Huettner, C. S., Radomska, H. S., Gonzalez, D. A., Tenen, D. G., & Akashi, K. (2002). Differential regulation of the human and murine CD34 genes in hematopoietic stem cells. Proceedings of the National Academy of Sciences, 99(9), 6246-6251.

Availability: In stock

Size	Price	Qty
25 μg	$80.00
100 μg	$265.00

Additional A7R34 Formats

Cat.No.	Format	Starting From
19212-60	PE	$ 60.00
19212-70	PerCP-Cyanine5.5	$ 75.00
19212-77	PE-Cyanine7	$ 95.00
19212-40	BG Violet 450	$ 135.00
19212-20	Purified	$ 135.00
19212-50	FITC	$ 40.00
19212-30	Biotin	$ 45.00
19212-80	APC	$ 80.00