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Anti-Human Perforin PE



Catalog Number : 84811-60

Description

The dG9 monoclonal antibody specifically reacts with human perforin, a cytolytic mediator found in the cytoplasmic granules of cytotoxic T (CTL) and natural killer (NK) cells. Perforin is integral molecule in targeted cell lysis and utilized in the immune system’s reaction to tumors and virus infections.

Additional Information

Clone:
dG9 (delta G9)
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
IgG2b, kappa
Research Interest: Innate Immunity, Adaptive Immunity, Apoptosis
Cell Type: NK and NKT Cells, T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Hameed, A., Olsen, K. J., Cheng, L., Fox 3rd, W. M., Hruban, R. H., & Podack, E. R. (1992). Immunohistochemical identification of cytotoxic lymphocytes using human perforin monoclonal antibody. The American journal of pathology140(5), 1025.

Schlesinger, B. C., & Cheng, L. (1994). Characterization of a novel monoclonal antibody against human perforin using transfected cell lines. Immunology81(2), 291.

Wood, S. M., Meeths, M., Chiang, S. C., Bechensteen, A. G., Boelens, J. J., Heilmann, C., ... & Bryceson, Y. T. (2009). Different NK cell–activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood114(19), 4117-4127.


Availability: In stock

Size Price Qty
25 tests
$140.00
100 tests
$310.00
Additional dG9 (delta G9) Formats
Cat.No. Format Starting From
84811-60PE $ 140.00