Anti-Human/Mouse ROR gamma (t) PE
Catalog Number : 77711-60
description
The AFKJS-9 monoclonal antibody reacts with the mouse ROR gamma(t) and ROR gamma proteins, members of the retinoic acid-related orphan receptor family (ROR). These transcription factors are ligand-dependent and the ROR gamma(t) isoform is expressed exclusively in the Th17 cells of the lymphoid organs it differs from ROR gamma by three amino acids
Additional Information
Clone:
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AFKJS-9
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Format:
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PE
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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IgG2a
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Research Interest: | Adaptive Immunity |
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Cell Type: | T Cells |
Application: | FC |
Clone: | AFKJS-9 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Schmutz, S., Bosco, N., Chappaz, S., Boyman, O., Acha-Orbea, H., Ceredig, R., ... & Finke, D. (2009). Cutting edge: IL-7 regulates the peripheral pool of adult RORγ+ lymphoid tissue inducer cells. The Journal of Immunology, 183(4), 2217-2221. Sun, Z., Unutmaz, D., Zou, Y. R., Sunshine, M. J., Pierani, A., Brenner-Morton, S., ... & Littman, D. R. (2000). Requirement for RORγ in thymocyte survival and lymphoid organ development. Science, 288(5475), 2369-2373. He, Y. W., Deftos, M. L., Ojala, E. W., & Bevan, M. J. (1998). RORγt, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity, 9(6), 797-806. |