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Anti-Human/Mouse ROR gamma (t) APC



Catalog Number : 77711-80

Description

The AFKJS-9 monoclonal antibody reacts with the mouse ROR gamma(t) and ROR gamma proteins, members of the retinoic acid-related orphan receptor family (ROR). These transcription factors are ligand-dependent and the ROR gamma(t) isoform is expressed exclusively in the Th17 cells of the lymphoid organs it differs from ROR gamma by three amino acids

Additional Information

Clone:
AFKJS-9
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
IgG2a
Research Interest: Adaptive Immunity
Cell Type: T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Schmutz, S., Bosco, N., Chappaz, S., Boyman, O., Acha-Orbea, H., Ceredig, R., ... & Finke, D. (2009). Cutting edge: IL-7 regulates the peripheral pool of adult RORγ+ lymphoid tissue inducer cells. The Journal of Immunology183(4), 2217-2221.

Sun, Z., Unutmaz, D., Zou, Y. R., Sunshine, M. J., Pierani, A., Brenner-Morton, S., ... & Littman, D. R. (2000). Requirement for RORγ in thymocyte survival and lymphoid organ development. Science288(5475), 2369-2373.

He, Y. W., Deftos, M. L., Ojala, E. W., & Bevan, M. J. (1998). RORγt, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity9(6), 797-806.


Availability: In stock

Size Price Qty
25 ug
$340.00
100 ug
$485.00
Additional AFKJS-9 Formats
Cat.No. Format Starting From
77711-60PE $ 340.00
77711-80APC $ 340.00