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Anti-Human/Mouse OCT3/4 PE



Catalog Number : 78011-60

Description

The EM92 monoclonal antibody reacts with human and mouse Oct 3/4, a POU family transcription factor. Oct 3/4 is encoded by the Pou5F1 gene and expressed on undifferentiated cells and lost in adult tissue. Fbx15, FGF-4, NANOG, Rex1, and UTF1 expression is regulated with Oct 3/4 and in many cases gene expression is regulated in concert with Sox2.

Additional Information

Clone:
EM92
Format:
PE
Applications:
FC
Reactivity:
Human, Mouse
Isotype:
Rat IgG2a, kappa
Research Interest: Stem Cell Research
Cell Type: Stem Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. cell131(5), 861-872.

Niwa, H., Miyazaki, J. I., & Smith, A. G. (2000). Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature genetics24(4), 372-376.

Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M., & Hamada, H. (1990). A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell60(3), 461-472.


Availability: In stock

Size Price Qty
25 ug
$170.00
100 ug
$360.00
Additional EM92 Formats
Cat.No. Format Starting From
78011-60PE $ 170.00
78011-20Purified $ 155.00