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Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified



Catalog Number : 80111-25

Description

The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1.

Additional Information

Clone:
2H5
Format:
SAFIRE Purified
Applications:
FC, FA, Neutralization
Reactivity:
Human, Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Chemotaxis, Angiogenesis
Cell Type: Dendritic Cells, Monocytes and Macrophages, T Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Luo, Y., Laning, J., Hayashi, M., Hancock, P. R., Rollins, B., & Dorf, M. E. (1994). Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1. The Journal of immunology153(8), 3708-3716.

Bost, K. L., Bento, J. L., Petty, C. C., Schrum, L. W., Hudson, M. C., & Marriott, I. (2001). Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.Journal of Interferon & Cytokine Research21(5), 297-304.

Taal, M. W., Chertow, G. M., Rennke, H. G., Gurnani, A., Jiang, T., Shahsafaei, A., ... & Mackenzie, H. S. (2001). Mechanisms underlying renoprotection during renin-angiotensin system blockade. American Journal of Physiology-Renal Physiology280(2), F343-F355.


Availability: In stock

Size Price Qty
50μg
$100.00
500ug
$310.00
Additional 2H5 Formats
Cat.No. Format Starting From
80111-25SAFIRE Purified $ 100.00