Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified

Grouped product items
Size	Price	Qty
50μg	$170.00
500ug	$530.00

Additional 2H5 Formats

Cat.No.	Format	Starting From
80111-25	SAFIRE Purified	$ 170.00

Catalog Number : 80111-25

description

The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1.

Additional Information

Clone:	2H5
Format:	SAFIRE Purified
Applications:	FC, FA, Neutralization
Reactivity:	Human, Mouse, Rat
Isotype:	Armenian Hamster IgG
Research Interest:	Angiogenesis
Cell Type:	Dendritic Cells, Macrophage / Monocyte, T Cells
Application:	FC, FA, Neutralization
Clone:	2H5
Preparation:	The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:	Phosphate-buffered aqueous solution, ph7.2.
References:	Luo, Y., Laning, J., Hayashi, M., Hancock, P. R., Rollins, B., & Dorf, M. E. (1994). Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1. The Journal of immunology, 153(8), 3708-3716. Bost, K. L., Bento, J. L., Petty, C. C., Schrum, L. W., Hudson, M. C., & Marriott, I. (2001). Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.Journal of Interferon & Cytokine Research, 21(5), 297-304. Taal, M. W., Chertow, G. M., Rennke, H. G., Gurnani, A., Jiang, T., Shahsafaei, A., ... & Mackenzie, H. S. (2001). Mechanisms underlying renoprotection during renin-angiotensin system blockade. American Journal of Physiology-Renal Physiology, 280(2), F343-F355.