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Anti-Human/Mouse CD27 SAFIRE Purified



Catalog Number : 09321-25

Description

The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.3A10 antibody is cross-reactive with human, mouse and rat CD27.

Additional Information

Clone:
LG.3A10
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human, Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Adaptive Immunity, Apoptosis
Cell Type: T Cells, B Cells, NK and NKT Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Hendriks, J., Xiao, Y., & Borst, J. (2003). CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. The Journal of experimental medicine198(9), 1369-1380.

Sakanishi, T., & Yagita, H. (2010). Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice.Biochemical and biophysical research communications393(4), 829-835.

Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M., & Borst, J. (1995). Novel mAbs reveal potent co-stimulatory activity of murine CD27. International immunology7(4), 551-557.


Availability: In stock

Size Price Qty
50 ug
$110.00
500 ug
$360.00
Additional LG.3A10 Formats
Cat.No. Format Starting From
09321-25SAFIRE Purified $ 110.00