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Anti-Human IL-4 PE



Catalog Number : 81111-60

Description

The 8D4-8 monoclonal antibody specifically reacts with human IL-4, expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The 8D4-8 antibody neutralizes the IL-4 cytokine.

Additional Information

Clone:
8D4-8
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity, Adaptive Immunity, Cytokines & Growth Factors
Cell Type: T Cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Bird, C., Wadhwa, M., & Thorpe, R. (1991). Development of immunoassays for human interleukin 3 and interleukin 4, some of which discriminate between different recombinant DNA-derived molecules. Cytokine3(6), 562-567.

Prussin, C., & Metcalfe, D. D. (1995). Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. Journal of immunological methods188(1), 117-128.

Kon, O. M., Sihra, B. S., Till, S. J., Corrigan, C. J., Kay, A. B., & Grant, J. A. (1998). Unstimulated basophils in atopic and nonatopic subjects express intracellular interleukin‐4: detection by flow cytometry. Allergy53(9), 891-896.


Availability: In stock

Size Price Qty
25 tests
$110.00
100 tests
$250.00
Additional 8D4-8 Formats
Cat.No. Format Starting From
81111-60PE $ 110.00
81111-77PE-Cyanine7 $ 135.00