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Anti-Human IFN gamma SAFIRE Purified



Catalog Number : 80821-25

Description

The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-γ.

Additional Information

Clone:
NIB42
Format:
SAFIRE Purified
Applications:
FC, Neutralization,
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity, Adaptive Immunity, Cytokines & Growth Factors
Cell Type: Th1 cells, NK and NKT Cells, T Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays. Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.

Meager, A., Parti, S., Barwick, S., Spragg, J., & O'hagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon. Journal of interferon research4(4), 619-625.


Availability: In stock

Size Price Qty
50 ug
$110.00
500 ug
$310.00
Additional NIB42 Formats
Cat.No. Format Starting From
80821-25SAFIRE Purified $ 110.00