Anti-Human HLA-DR Purified
Catalog Number : 74111-20
description
The LN3 monoclonal antibody specifically reacts with the human leukocyte antigen-DR (HLA-DR), a MHC class II heterodimeric surface glycoprotein. HLA-DR is expressed on the antigen presenting surfaces of monocytes, macrophages, dendritic cells, activated T cells, and B cells. It is integral to peptide presentation to CD4+ T cells.
Additional Information
Clone: | LN3 |
Format: | Purified |
Applications: | FC |
Reactivity: | Human |
Isotype: | Mouse IgG2b, kappa |
| Research Interest: | Adaptive Immunity |
|---|---|
| Cell Type: | B Cells, Macrophage / Monocyte, T Cells |
| Application: | FC |
| Clone: | LN3 |
Preparation: | The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Norton, A. J., & Isaacson, P. G. (1987). Detailed phenotypic analysis of B-cell lymphoma using a panel of antibodies reactive in routinely fixed wax-embedded tissue. The American journal of pathology, 128(2), 225. Hua, Z. X., Tanaka, K. E., Tazelaar, H. D., Myers, J., Markowitz, G. S., & Borczuk, A. C. (1998). Immunoreactivity for LN2 and LN3 distinguishes small cell carcinomas from non-small cell carcinomas in the lung. Human pathology,29(12), 1441-1446. Ioachim, H. L., Pambuccian, S. E., Hekimgil, M., Giancotti, F. R., & Dorsett, B. H. (1996). Lymphoid monoclonal antibodies reactive with lung tumors: diagnostic application. The American journal of surgical pathology, 20(1), 64-71. |