Anti-Human gamma delta TCR SAFIRE Purified
Additional B1.1 Formats
| Cat.No. | Format | Starting From |
|---|---|---|
| 81311-25 | SAFIRE Purified | $ 220.00 |
Catalog Number : 81311-25
description
The B1.1 monoclonal antibody specifically reacts with the gamma delta T cell receptor, a receptor complex composed of the two disulfide linked transmembrane glycoproteins. The complex is expressed on peripheral T cell subsets and thymocytes and is reported to be involved in the recognition of tumor and bacterial antigens. Research is being conducted to determine its role in antigen presentation and autoimmune response regulation.
Additional Information
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Clone:
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B1.1
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Format:
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SAFIRE Purified
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Applications:
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FC, FA
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity, Innate Immunity |
|---|---|
| Cell Type: | T Cells |
| Application: | FC, FA |
| Clone: | B1.1 |
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Preparation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Bonneville, M., O'Brien, R. L., & Born, W. K. (2010). γδ T cell effector functions: a blend of innate programming and acquired plasticity. Nature Reviews Immunology, 10(7), 467-478. De Libero, G. (1997). Sentinel function of broadly reactive human γδ T cells.Immunology today, 18(1), 22-26. Stinissen, P., Vandevyver, C., Medaer, R., Vandegaer, L., Nies, J., Tuyls, L., ... & Zhang, J. (1995). Increased frequency of gamma delta T cells in cerebrospinal fluid and peripheral blood of patients with multiple sclerosis. Reactivity, cytotoxicity, and T cell receptor V gene rearrangements. The Journal of Immunology, 154(9), 4883-4894. |