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Anti-Human CD95 (APO-1/Fas) SAFIRE Purified



Catalog Number : 08011-25

Description

The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.

Additional Information

Clone:
EOS9.1
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgM, kappa
Cell Type: T Cells, Monocytes and Macrophages, B Cells, NK and NKT Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Nagata, S., & Golstein, P. (1995). The Fas death factor. Science267(5203), 1449-1456.

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Zhang, P., Sun, D., Ke, Y., Kaplan, H. J., & Shao, H. (2007). The net effect of costimulatory blockers is dependent on the subset and activation status of the autoreactive T cells. The Journal of Immunology178(1), 474-479.


Availability: In stock

Size Price Qty
50 ug
$110.00
500 ug
$400.00
Additional EOS9.1 Formats
Cat.No. Format Starting From
08011-25SAFIRE Purified $ 110.00