Anti-Human CD7 FITC
Catalog Number : 49111-50
description
The 4H9 monoclonal antibody specifically binds to human CD7, a 40 kDa type I transmembrane glycoprotein known as Leu-9 or gp40. CD7 is found on the surfaces of T cells, NK cells, and acute lymphocytic leukemia cells. It is reported to be involved in modulating cytokine secretion and cellular adhesion.
Additional Information
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Clone:
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4H9
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Format:
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FITC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG2a, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells, NK and NKT Cells |
| Application: | FC |
| Clone: | 4H9 |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Davis, A. L., McKenzie, J. L., & Hart, D. N. (1988). HLA-DR-positive leucocyte subpopulations in human skin include dendritic cells, macrophages, and CD7-negative T cells. Immunology, 65(4), 573. Rabinowich, H., Pricop, L., Herberman, R. B., & Whiteside, T. L. (1994). Expression and function of CD7 molecule on human natural killer cells. The Journal of Immunology, 152(2), 517-526. Link, M., Warnke, R., Finlay, J., Amylon, M., Miller, R., Dilley, J., & Levy, R. (1983). A single monoclonal antibody identifies T-cell lineage of childhood.Blood, 62(4), 722-728. |