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Anti-Human CD64 (Fc gamma Receptor 1) SAFIRE Purified



Catalog Number : 06711-25

Description

The 10.1 monoclonal antibody specifically reacts with human CD64, a 75kDA type I transmembrane glycoprotein that is the high affinity receptor for IgG. CD64 is expressed on macrophages and dendritic cells and is involved in antibody-dependent cellular toxicity, cytokine release phagocytosis, and endocytosis. The 10.1 antibody is reported to recognize the EC3 epitope of CD64.

Additional Information

Clone:
10.1
Format:
SAFIRE Purified
Applications:
FC, FA, IHC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Innate Immunity
Cell Type: Monocytes and Macrophages, Dendritic Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Dougherty, G. J., Selvendran, Y., Murdoch, S., Palmer, D. G., & Hogg, N. (1987). The human mononuclear phagocyte high‐affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1. European journal of immunology,17(10), 1453-1459.

Indik, Z. K., Hunter, S., Huang, M. M., Pan, X. Q., Chien, P., Kelly, C., ... & Schreiber, A. D. (1994). The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI. Experimental hematology22(7), 599-606.


Availability: In stock

Size Price Qty
50 ug
$120.00
500 ug
$385.00
Additional 10.1 Formats
Cat.No. Format Starting From
06711-25SAFIRE Purified $ 120.00