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Anti-Human CD62P (P-Selectin) PE



Catalog Number : 04711-60

Description

The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.

Additional Information

Clone:
AK-4
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity, Angiogenesis
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Johnson-Tidey, R. R., McGregor, J. L., Taylor, P. R., & Poston, R. N. (1994). Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1.The American journal of pathology144(5), 952.


Availability: In stock

Size Price Qty
25 tests
$110.00
100 tests
$240.00
Additional AK-4 Formats
Cat.No. Format Starting From
04711-60PE $ 110.00