Anti-Human CD5 APC
Catalog Number : 09111-80
description
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
Additional Information
Clone:
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UCHT2
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Format:
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APC
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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Research Interest: | Adaptive Immunity |
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Cell Type: | B Cells, T Cells |
Application: | FC |
Clone: | UCHT2 |
Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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McMichael, A. J. (1987). Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA. Lankester, A. C., van Schijndel, G. M., Cordell, J. L., van Noesel, C. J., & van Lier, R. A. (1994). CD5 is associated with the human B cell antigen receptor complex. European journal of immunology, 24(4), 812-816. Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... & A't Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry, 57(12), 1159-1167. |