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Anti-Human CD48 SAFIRE Purified



Catalog Number : 10511-25

Description

The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.

Additional Information

Clone:
156-4H9
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human
Isotype:
Mouse IgG1
Research Interest: Adaptive Immunity, Innate Immunity, Stem Cell Research
Cell Type: B Cells, Monocytes and Macrophages, T Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

González-Álvaro, I., Domínguez-Jiménez, C., Ortiz, A. M., Núñez-González, V., Roda-Navarro, P., Fernández-Ruiz, E., ... & Sánchez-Madrid, F. (2006). Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production. Arthritis research & therapy8(4), R88.

Katagiri, T., Qi, Z., Ohtake, S., & Nakao, S. (2011). GPI‐anchored protein‐deficient T cells in patients with aplastic anemia and low‐risk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology86(3), 226-236.

Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., & Thorley-Lawson, D. A. (1991). Expression of the Blast-1 activation/adhesion molecule and its identification as CD48. The Journal of immunology146(7), 2192-2200.


Availability: In stock

Size Price Qty
50 ug
$110.00
500 ug
$400.00
Additional 156-4H9 Formats
Cat.No. Format Starting From
10511-25SAFIRE Purified $ 110.00