Anti-Human CD357 (AITR/GITR) PE
Catalog Number : 39621-60
description
The AITR monoclonal antibody reacts with human CD357, also known as activation inducible TNFR (AITR) family member. It is expressed on activated lymphocytes and plays a key role in dominant immunological self-tolerance.
Additional Information
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Clone:
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AITR
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Format:
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PE
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Applications:
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FC
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Reactivity:
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | Adaptive Immunity |
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| Cell Type: | T Cells |
| Application: | FC |
| Clone: | AITR |
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Preparation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Hu, X., Liu, C., An, J., Shen, Y., Hu, Y., Jiang, J., ... & Zhang, X. (2016). Development of a Novel Functional Monoclonal Antibody to Human CD275: Characterization and Biological Activity. Monoclonal antibodies in immunodiagnosis and immunotherapy, 35(1), 18-24. Youngnak‐Piboonratanakit, P., Tsushima, F., Otsuki, N., Igarashi, H., Omura, K., & Azuma, M. (2006). Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues. Scandinavian journal of immunology, 63(3), 191-198. Yao, S., Zhu, Y., Zhu, G., Augustine, M., Zheng, L., Goode, D. J., ... & Flies, D. (2011). B7-h2 is a costimulatory ligand for CD28 in human. Immunity, 34(5), 729-740. |