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Anti-Human CD3 APC



Catalog Number : 05141-80

Description

The SK7 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes.
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Human peripheral blood lymphocytes were stained with APC SK7 with relevant isotype control in Red.
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Additional Information

Clone:
SK7
Format:
APC
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: NK and NKT Cells, T Cells, Treg cells, Th17 cells
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., ... & Terhorst, C. (1988). Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies. Blood71(3), 603-612.

Haynes, B. F. (1986). Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. In Leukocyte typing II (pp. 3-30). Springer New York.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... & A't Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Journal of Histochemistry & Cytochemistry57(12), 1159-1167.


Availability: In stock

Size Price Qty
25 tests
$145.00
100 tests
$310.00
500 tests
$1,350.00
Additional SK7 Formats
Cat.No. Format Starting From
05141-80APC $ 145.00
05141-77PE-Cyanine7 $ 145.00
05141-40BG Violet 450 $ 120.00
05141-50FITC $ 80.00
05141-60PE $ 135.00
05141-87APC-Cyanine7 $ 135.00