Anti-Human CD275 (B7-H2) PE

Grouped product items
Size Price Qty
100 tests
$420.00

Additional MIH12 Formats

Cat.No. Format Starting From
27811-60 PE $ 420.00
Catalog Number : 27811-60

description

The MIH12 monoclonal antibody reacts with human CD275, also known as B7-H2, B7h, B7RP-1, and ICOS ligand. CD275 is expressed on macrophages, monocytes, and dendritic cells. It binds to the ICOS (CRP-1 or AILIM) receptor expressed on activated T cells and interacts with the T cell costimulation pathway.

Additional Information

Clone:
MIH12
Format:
PE
Applications:
FC
Reactivity:
Human
Isotype:
Mouse IgG1, kappa
Research Interest: Adaptive Immunity
Cell Type: Macrophage / Monocyte
Application: FC
Clone: MIH12
Preparation:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References:

Hu, X., Liu, C., An, J., Shen, Y., Hu, Y., Jiang, J., ... & Zhang, X. (2016). Development of a Novel Functional Monoclonal Antibody to Human CD275: Characterization and Biological Activity. Monoclonal antibodies in immunodiagnosis and immunotherapy35(1), 18-24.

Youngnak‐Piboonratanakit, P., Tsushima, F., Otsuki, N., Igarashi, H., Omura, K., & Azuma, M. (2006). Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues. Scandinavian journal of immunology63(3), 191-198.

Yao, S., Zhu, Y., Zhu, G., Augustine, M., Zheng, L., Goode, D. J., ... & Flies, D. (2011). B7-h2 is a costimulatory ligand for CD28 in human. Immunity34(5), 729-740.

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