Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Anti-Human CD27 SAFIRE Purified



Catalog Number : 09331-25

Description

The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.7F9 antibody is cross-reactive human, mouse, and rat CD27.

Additional Information

Clone:
LG.7F9
Format:
SAFIRE Purified
Applications:
FC, FA
Reactivity:
Human, Mouse, Rat
Isotype:
Armenian Hamster IgG
Research Interest: Adaptive Immunity, Apoptosis
Cell Type: T Cells, B Cells, NK and NKT Cells
Preparation:
The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
References:

Tesselaar, K., Xiao, Y., Arens, R., van Schijndel, G. M., Schuurhuis, D. H., Mebius, R. E., ... & van Lier, R. A. (2003). Expression of the murine CD27 ligand CD70 in vitro and in vivo. The journal of immunology170(1), 33-40.

Lee, E. M., Hurh, S., Cho, B., Oh, K. H., Kim, S. U., Surh, C. D., ... & Ahn, C. (2013). CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T cell death. Stem cell research & therapy4(3), 56.

Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M., & Borst, J. (1995). Novel mAbs reveal potent co-stimulatory activity of murine CD27. International immunology7(4), 551-557.


Availability: In stock

Size Price Qty
500 ug
$330.00
Additional LG.7F9 Formats
Cat.No. Format Starting From
09331-25SAFIRE Purified $ 330.00